Mtm1 CLIA Kit for Rat(Rattus norvegicus) | EIAab.comMtm1 CLIA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Mtm1(Gene name) > Rat

Mtm1 (Gene name),

Myotubularin (Protein name ), MTM1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Mtm1;

Protein name:

Myotubularin;

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with MTMR12; the interaction modulates MTM1 intracellular localization. Interacts with MLL (via SET domain). Interacts with DES in skeletal muscle but not in cardiac muscle.

Function:

Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis.

Subcellular Location:

Cytoplasm Cell membrane Peripheral membrane protein Cell projection filopodium Cell projection ruffle Late endosome Localizes as a dense cytoplasmic network. Also localizes to the plasma membrane, including plasma membrane extensions such as filopodia and ruffles. Predominantly located in the cytoplasm following interaction with MTMR12. Recruited to the late endosome following EGF stimulation.

Protein Attributes:

Sequence length:

602

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

602:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q6AXQ4

UniGene:

Rn.23921

Pfam:

PF02893

String:

Q6AXQ4

KEGG:

rno:288762

Uniprot:

Q6AXQ4

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ELISA Kit for Rat Myotubularin

Cat.:

E15150m

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96T

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ELISA Kit for Rat Myotubularin

Cat.:

E15150h

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96T

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ELISA Kit for Rat Myotubularin

Cat.:

E15150r

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Packing:

96T

ELISA Kit for Rat Myotubularin

Cat.:

E15150b

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Packing:

96T

CLIA Kit for Rat Myotubularin

Cat.:

U15150h

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Packing:

96T

CLIA Kit for Rat Myotubularin

Cat.:

U15150r

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Packing:

96T

CLIA Kit for Rat Myotubularin

Cat.:

U15150b

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Packing:

96T

CLIA Kit for Rat Myotubularin

Cat.:

U15150m

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Packing:

96T

Polyclonal Antibody for Rat Myotubularin

Cat.:

P15150Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Myotubularin

Cat.:

P15150Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Myotubularin

Cat.:

P15150Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat Myotubularin

Protein for Rat Myotubularin

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue: Kidney.
tissue: Testis.

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